library.onepin.app/vladonix Peptide Education Library

Education only, not medical advice◆ 21+◆ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Bioregulators

Bioregulators Khavinson bioregulator tripeptide Not FDA-approved · investigational

Vladonix

Vladonix (Khavinson)

Khavinson bioregulator tripeptideThymus gland regulatorImmune maturation modulator

Vladonix (Lys-Glu-Asp) is a Khavinson bioregulator tripeptide targeting the thymus gland, similar to Thymalin but as a synthetic tripeptide rather than a gland extract. It supports thymic epithelial cell function, T-cell development, and immune competence maintenance.

Quick Start

Route

SubQ injection

Start low

5 mg daily

Frequency

Daily for 10-20 day course

Timing

No fasting required

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

❋

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first

Quick Start

Conservative start

5 mg daily · SubQ injection · Daily for 10-20 day course

Lowest starting point. Hold about a week to assess tolerance before stepping up.

5 mg daily

Daily for 10-20 day course

Standard

Thymus Gland Extraction

20-40 mg · Oral · Daily

human study · Khavinson V, Morozov V. Peptides of pineal gland and thymus prolong human life. Neuro Endocrinol Lett. 2003;24(3-4):233-240.

20-40 mg

Daily

Reconstitution CalculatorU-100

Vial strength

BAC water

Target dose

050100u

Draw to

— units

◆

How it works

Vladonix modulates gene expression in thymic epithelial cells, supporting the thymic microenvironment necessary for T-cell maturation and selection.

What to expect

Early

Days 1–7

Days 1-10: Gene changes initiated.

Mid

Weeks 2–4

Weeks 2-8: Thymic gene programs established.

Later

Weeks 4–12

Months: Sustained immune support.

Evidence

HumanPresent

AnimalPresent

In-vitroPresent

2003Peptides of pineal gland and thymus prolong human life · Khavinson VKh, Morozov VG, Neuroendocrinology Letters ↗peer reviewed

2013Peptide bioregulators: the new class of geroprotectors. Message 2. Clinical studies results · Khavinson VKh, Kuznik BI, Ryzhak GA, Advances in Gerontology ↗review

2013Peptide bioregulators: the new class of geroprotectors. Communication 1. Results of experimental studies · Khavinson VKh, Kuznik BI, Ryzhak GA, Advances in Gerontology ↗review

2022Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line · Linkova NS, Drobintseva AO, Orlova OA, et al, International Journal of Molecular Sciences ↗peer reviewed

The honest take

◆

Thymic rejuvenation

Synthetic tripeptide alternative to Thymalin gland extract. Targets same thymic gene expression pathways.

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Safe & synergistic

TA-1Both target thymus. Vladonix bioregulatory + TA-1 direct immune modulation.

ThymalinBoth thymus bioregulators. Can run in sequence for extended support.

Keep separate

ALL (syringe)PIN ALONE.

GHK-CuCopper degrades bioregulators.

Side effects & safety

Commonly reported

Very well tolerated

Less common & notes

Autoimmune caution.

Pharmacokinetics

Illustrative plasma concentration · 24 h

Half-life

0.5h

Peak · Tmax

0.05h

Elimination

2.5h

Activity

Weeks to months (epigenetic thymic gene expression changes persist beyond dosing course)

Storage. Standard BAC water 2-8C. 21-28 days.

Regulatory status

Not FDA-approved. Research peptide.

Put it to work

Calculate, log & track

Open Vladonix straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Vladonix in the app →

Go deeper

The guide & community

The complete Vladonix walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗

Open in app Community