Bioregulators Khavinson bioregulator tripeptideNot FDA-approved · research compound

Vladonix

Vladonix (Khavinson)

Evidence: Studied in humans. Example dose: finalize with a provider. Not a fact-check stamp.

10 mg daily SubQ 10-20 day course. Capsule form.

20-40 mg Oral Daily

Thymus gland regulatorImmune maturation modulator

Vladonix (Lys-Glu-Asp) is a Khavinson bioregulator tripeptide targeting the thymus gland, similar to Thymalin but as a synthetic tripeptide rather than a gland extract. It supports thymic epithelial cell function, T-cell development, and immune competence maintenance.

Quick Start

Route

SubQ injection

Start low

10 mg SubQ

Frequency

10-20 day course. Capsule form.

Timing

No fasting required

Starting dose. 10 mg — Daily

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

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Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first

Conservative start

10 mg daily · SubQ injection · 10-20 day course. Capsule form.

conservative starter

10 mg daily

10-20 day course. Capsule form.

Standard

Thymus Gland Extraction

20-40 mg · Oral · Daily

human study · Khavinson V, Morozov V. Peptides of pineal gland and thymus prolong human life. Neuro Endocrinol Lett. 2003;24(3-4):233-240.

A 'Cytomax' (natural extract), compared to 'Cytogens' (synthetics). Takes longer to build up but effects are considered more profound and longer-lasting.

20-40 mg

Daily

Reconstitution CalculatorU-100

Vial strength

BAC water

Vials in this mix

Syringe size

Target dose

050100u

Draw to

— units

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I will split this dose across more than one syringe

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How it works

Vladonix modulates gene expression in thymic epithelial cells, supporting the thymic microenvironment necessary for T-cell maturation and selection.

What to expect

Early

Days 1–7

Days 1-10: Gene changes initiated.

Mid

Weeks 2–4

Weeks 2-8: Thymic gene programs established.

Later

Weeks 4–12

Months: Sustained immune support.

Evidence

HumanPresent

AnimalPresent

In-vitroPresent

Claims we could not support

No abstract we checked supports these for this molecule at this route. That is not the same as saying they are false — it marks where the evidence is missing.

Exact-molecule abstract evidence. ESearch was run and 4 source-candidate PMIDs were EFetch-checked; no usable exact-molecule abstract sentence was found.

Dose/route: 10 mg daily; SubQ injection; 10-20 day course. Capsule form.. No selected live abstract sentence verified this complete regimen.

Mechanism as written in source JSON. No selected live abstract sentence verified the complete mechanism at the card formulation/route and relevant population/model.

Primary safety claim as written in source JSON. No selected live abstract sentence verified the complete safety claim for this exact formulation and route.

The honest take

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Thymic rejuvenation

Synthetic tripeptide alternative to Thymalin gland extract. Targets same thymic gene expression pathways.

Interactions & stacking

Two different questions: what is documented about running these together, and what is documented about drawing them into the same syringe. A good pharmacological partner can still have to be pinned separately.

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Pin alone. Vladonix must not share a syringe with anything else, whatever the pharmacology says. PIN ALONE.

Documented together

TA-1Both target thymus. Vladonix bioregulatory + TA-1 direct immune modulation.

ThymalinBoth thymus bioregulators. Can run in sequence for extended support.

Keep separate

GHK-CuCopper degrades bioregulators.

Check any specific pair in the Stack & Interaction Checker, which answers both questions separately. Absence of a documented conflict is not evidence of safety.

Side effects & safety

Commonly reported

Very well tolerated

Less common & notes

Autoimmune caution.

Pharmacokinetics

Illustrative plasma concentration · 2.0 h

Half-life

0.5h

Peak · Tmax

0.05h

Elimination

2.5h

Bioavailability

~100%

SubQ

Duration of action

Weeks to months (epigenetic thymic gene expression changes persist beyond dosing course)

Clearance

Enzymatic degradation (aminopeptidases)

Storage. Standard BAC water 2-8C. 21-28 days.

Regulatory status

Not FDA-approved. Research peptide.

Put it to work

Calculate, log & track

Open Vladonix straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Vladonix in the app →

Go deeper

The guide & community

The complete Vladonix walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

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