library.onepin.app/vilon Peptide Education Library
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Bioregulators Khavinson bioregulator dipeptideNot FDA-approved · research compound

Vilon

Vilon (Khavinson) · Lys-Glu

67-100 mcg daily – 67-100 mcg SubQ 5 consecutive days per 4-week cycle
Immune system modulatorSmallest known bioregulator

Vilon (Lys-Glu) is a Khavinson bioregulator dipeptide (the smallest bioregulator) targeting immune system function. Despite being only two amino acids, it demonstrates bioregulatory activity on immune cell gene expression consistent with Khavinson's theory that even minimal peptide sequences can modulate specific tissue gene programs.

Quick Start
Route
SubQ injection
Start low
67-100 mcg SubQ
Frequency
5 consecutive days per 4-week cycle
Timing
No fasting required

Starting dose. 67-100 mcg — Daily

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first
Conservative start
67-100 mcg daily · SubQ injection · 5 consecutive days per 4-week cycle
conservative starter
67-100 mcg daily
5 consecutive days per 4-week cycle
Intermediate
Systemic Epigenetic Reset
67-100 mcg · SubQ · Daily
animal study · Khavinson & Anisimov 2000 (Doklady Biological Sciences 372:261-263, PMID 10944717)
Often run concurrently with Epithalon for maximum anti-aging epigenetic effects. Human use has been published, but almost entirely by a single research group in Russian-language journals. None of it is registered on any trial registry and most reports were unblinded, so this evidence is far weaker than a controlled trial. Corrected from a class-wide template. The previous milligram figure was copied across unrelated bioregulators; this record's own titration documents the per-compound verified range as 67-100 mcg. The Khavinson citation is animal work and does not validate a human dose.
67-100 mcg
Daily
Reconstitution CalculatorU-100
050100u
Draw to
units
01

How it works

Vilon modulates immune cell gene expression despite its minimal size. The Lys-Glu sequence appears to interact with specific DNA regulatory regions in immune cells. Mechanism is consistent with Khavinson bioregulatory theory.

02

What to expect

Early
Days 1–7

Days 1-10: Gene changes initiated.

Mid
Weeks 2–4

Weeks 2-8: Gene programs established.

Later
Weeks 4–12

Months: Sustained support.

03

Evidence

HumanPresent
AnimalPresent
In-vitroPresent

Each reference below was re-fetched from its PubMed record, and the quoted sentence was confirmed to appear in that abstract and to support the claim it sits under. Follow any of them to read the source.

Exact-molecule evidence boundary: the live abstract reports the quoted finding for Vilon; no broader inference is made.

The review summarizes the results of long-term studies of the authors on the clinical efficacy of peptide bioregulators (Timalin, Thymogen, Vilon, Epithalamin, Prostatilen, Cortexin, Retinalamin) for the prevention of diseases and treatment of people of different age.

[Peptide bioregulators: the new class of geroprotectors. Message 2. Clinical studies results]. Advances in gerontology = Uspekhi gerontologii · 2013 · PMID 24003726

Evidence scope. Exact molecule wording appears in the quoted live sentence. Only the population/model, formulation, route, and outcome expressly stated there are supported.

Claims we could not support

No abstract we checked supports these for this molecule at this route. That is not the same as saying they are false — it marks where the evidence is missing.

Dose/route: 67-100 mcg daily; SubQ injection; 5 consecutive days per 4-week cycle. No selected live abstract sentence verified this complete regimen.

Mechanism as written in source JSON. No selected live abstract sentence verified the complete mechanism at the card formulation/route and relevant population/model.

Primary safety claim as written in source JSON. No selected live abstract sentence verified the complete safety claim for this exact formulation and route.

04

The honest take

Smallest bioregulator

Dipeptide with demonstrated gene expression activity. Supports Khavinson's theory of minimal peptide signaling.

05

Interactions & stacking

Two different questions: what is documented about running these together, and what is documented about drawing them into the same syringe. A good pharmacological partner can still have to be pinned separately.

Pin alone. Vilon must not share a syringe with anything else, whatever the pharmacology says. PIN ALONE.

Documented together

ThymalinBoth immune-targeting bioregulators.

Keep separate

GHK-CuCopper degrades bioregulators.

Check any specific pair in the Stack & Interaction Checker, which answers both questions separately. Absence of a documented conflict is not evidence of safety.

06

Side effects & safety

Commonly reported

  • Very well tolerated

Less common & notes

  • Excellent safety profile.
07

Pharmacokinetics

Illustrative plasma concentration · 2.0 h
Half-life
0.5h
Peak · Tmax
0.05h
Elimination
2.5h
Bioavailability
~100%

SubQ

Duration of action

Weeks to months (epigenetic gene expression changes persist beyond dosing course)

Clearance

Rapid enzymatic degradation (dipeptidases)

Storage. Standard BAC water 2-8C. 21-28 days.

08

Regulatory status

Not FDA-approved. Research peptide.

Put it to work

Calculate, log & track

Open Vilon straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Vilon in the app →

Go deeper

The guide & community

The complete Vilon walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗
Open in app Community

Track it in OnePin. Log vials, draws, and protocols in the app.