library.onepin.app/vilon Peptide Education Library

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OnePin Peptide Library · Bioregulators

Bioregulators Khavinson bioregulator dipeptide Not FDA-approved · investigational

Vilon

Vilon (Khavinson) · Lys-Glu

Khavinson bioregulator dipeptideImmune system modulatorSmallest known bioregulator

Vilon (Lys-Glu) is a Khavinson bioregulator dipeptide (the smallest bioregulator) targeting immune system function. Despite being only two amino acids, it demonstrates bioregulatory activity on immune cell gene expression consistent with Khavinson's theory that even minimal peptide sequences can modulate specific tissue gene programs.

Quick Start

Route

SubQ injection

Start low

5 mg daily

Frequency

Daily for 10-20 day course

Timing

No fasting required

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

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Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first

Quick Start

Conservative start

5 mg daily · SubQ injection · Daily for 10-20 day course

Lowest starting point. Hold about a week to assess tolerance before stepping up.

5 mg daily

Daily for 10-20 day course

Intermediate

Systemic Epigenetic Reset

1-2 mg · SubQ · Daily

animal study · Khavinson & Anisimov 2000 (Doklady Biological Sciences 372:261-263, PMID 10944717)

1-2 mg

Daily

Reconstitution CalculatorU-100

Vial strength

BAC water

Target dose

050100u

Draw to

— units

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How it works

Vilon modulates immune cell gene expression despite its minimal size. The Lys-Glu sequence appears to interact with specific DNA regulatory regions in immune cells. Mechanism is consistent with Khavinson bioregulatory theory.

What to expect

Early

Days 1–7

Days 1-10: Gene changes initiated.

Mid

Weeks 2–4

Weeks 2-8: Gene programs established.

Later

Weeks 4–12

Months: Sustained support.

Evidence

HumanPresent

AnimalPresent

In-vitroPresent

2022Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line · Linkova NS, Drobintseva AO, Orlova OA, et al, International Journal of Molecular Sciences ↗peer reviewed

2013Peptide bioregulators: the new class of geroprotectors. Message 2. Clinical studies results · Khavinson VKh, Kuznik BI, Ryzhak GA, Advances in Gerontology ↗review

2013Peptide bioregulators: the new class of geroprotectors. Communication 1. Results of experimental studies · Khavinson VKh, Kuznik BI, Ryzhak GA, Advances in Gerontology ↗review

2010Peptide bioregulation of aging: results and prospects · Anisimov VN, Khavinson VKh, Biogerontology ↗review

The honest take

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Smallest bioregulator

Dipeptide with demonstrated gene expression activity. Supports Khavinson's theory of minimal peptide signaling.

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Safe & synergistic

ThymalinBoth immune-targeting bioregulators.

Keep separate

ALL (syringe)PIN ALONE.

GHK-CuCopper degrades bioregulators.

Side effects & safety

Commonly reported

Very well tolerated

Less common & notes

Excellent safety profile.

Pharmacokinetics

Illustrative plasma concentration · 24 h

Half-life

0.5h

Peak · Tmax

0.05h

Elimination

2.5h

Activity

Weeks to months (epigenetic gene expression changes persist beyond dosing course)

Storage. Standard BAC water 2-8C. 21-28 days.

Regulatory status

Not FDA-approved. Research peptide.

Put it to work

Calculate, log & track

Open Vilon straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Vilon in the app →

Go deeper

The guide & community

The complete Vilon walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗

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