library.onepin.app/crystagen Peptide Education Library

Education only, not medical advice◆ 21+◆ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Bioregulators

Bioregulators Khavinson bioregulator tripeptide Not FDA-approved · investigational

Crystagen

Crystagen (Khavinson)

Khavinson bioregulator tripeptideImmune system regulatorLymphocyte function modulator

Crystagen (Thr-Glu-Asp) is a Khavinson bioregulator tripeptide targeting the immune system, specifically supporting lymphocyte function and immune cell gene expression. It complements Thymalin (thymus) and Vladonix (thymus gland) by targeting peripheral immune cell function rather than thymic development.

Quick Start

Route

SubQ injection

Start low

5 mg daily

Frequency

Daily for 10-20 day course

Timing

No fasting required

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

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Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first

Quick Start

Conservative start

5 mg daily · SubQ injection · Daily for 10-20 day course

Lowest starting point. Hold about a week to assess tolerance before stepping up.

5 mg daily

Daily for 10-20 day course

Standard

Immune System Bioregulation

10-20 mg · Oral · Daily

anecdotal · community

10-20 mg

Daily

Reconstitution CalculatorU-100

Vial strength

BAC water

Target dose

050100u

Draw to

— units

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How it works

Crystagen modulates gene expression in lymphocytes and other immune cells, supporting cytokine production, cell proliferation pathways, and immune surveillance function.

What to expect

Early

Days 1–7

Days 1-10: Gene changes initiated.

Mid

Weeks 2–4

Weeks 2-8: Immune gene programs established.

Later

Weeks 4–12

Months: Sustained immune optimization.

Evidence

HumanPresent

AnimalPresent

In-vitroPresent

2010Peptide bioregulation of aging: results and prospects · Anisimov VN, Khavinson VKh, Biogerontology ↗review

2009Peptide regulation of aging: 35-year research experience · Khavinson VKh, Anisimov VN, Bulletin of Experimental Biology and Medicine ↗review

2003Peptidergic regulation of aging · Khavinson VKh, Bondarev IE, Butyugov AA, Bulletin of Experimental Biology and Medicine ↗peer reviewed

The honest take

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Immune optimization

Bioregulatory mechanism targeting lymphocyte gene expression.

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Safe & synergistic

TA-1Crystagen bioregulates immune gene expression, TA-1 directly modulates immune effector cells.

ThymalinThymalin targets thymus, Crystagen targets peripheral immune cells. Run in sequence.

Keep separate

ALL (syringe)PIN ALONE.

GHK-CuCopper degrades bioregulators.

Side effects & safety

Commonly reported

Very well tolerated

Less common & notes

Autoimmune caution.
Excellent safety profile.

Pharmacokinetics

Illustrative plasma concentration · 24 h

Half-life

0.5h

Peak · Tmax

0.05h

Elimination

2.5h

Activity

Weeks to months (immune gene expression changes persist long after peptide clearance)

Storage. Standard BAC water 2-8C. 21-28 days.

Regulatory status

Not FDA-approved. Research peptide.

Put it to work

Calculate, log & track

Open Crystagen straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Crystagen in the app →

Go deeper

The guide & community

The complete Crystagen walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗

Open in app Community