Education only, not medical advice◆21+◆Every dose is an example to finalize with a licensed provider
Immune
Thymulin
Thymulin Zinc
Evidence: Studied in humans. Example dose: finalize with a provider. Not a fact-check stamp.
Per protocol – 1-5 mgSubQDaily
Thymulin, also known as Facteur Thymique Serique (FTS) or serum thymic factor, is a nonapeptide hormone (Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn) produced exclusively by thymic epithelial cells. It is unique among thymic hormones in that it requires zinc to be biologically active - the zinc-thymulin complex (ZnFTS) is the functional form that binds to high-affinity receptors on T-cells.
Quick Start
Route
Subcutaneous (SubQ)
Start low
Per protocol SubQ
Frequency
Daily
Timing
No specific requirement - ensure adequate zinc status
SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.
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Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.
Tiered Protocols · lowest first
Conservative start
Per protocol · Subcutaneous (SubQ) · Daily
conservative starter
Per protocol
Daily
Intermediate
Zinc-Dependent T-Cell Support
1-5 mg · SubQ · Daily
animal study · Safieh-Garabedian et al. 2002 (Br J Pharmacol 136:947-955)
Biologically inactive without zinc. Ensure adequate dietary or supplemental zinc intake when utilizing this peptide. The study cited here is animal research. It shows the mechanism, not a human dose, and this amount is community practice rather than a trial result.
1-5 mg
Daily
Reconstitution CalculatorU-100
050100u
Draw to
— units
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01
How it works
Binds to specific high-affinity receptors on immature T-cell precursors in a zinc-dependent manner, triggering intracellular signaling cascades that promote T-cell differentiation, expression of T-cell surface markers (CD2, CD3, CD4, CD8), and functional maturation.
Modulates cytokine production by mature T-cells, promoting IL-2 secretion and shifting the Th1/Th2 balance. Also enhances NK cell cytotoxicity and modulates B-cell antibody production indirectly through T-helper cell regulation.
Exerts anti-inflammatory effects in the central nervous system by reducing microglial activation and pro-inflammatory cytokine production. Has been shown to reduce neuroinflammation in animal models of pain and neurodegenerative disease.
02
What to expect
Early
Days 1–7
Days 1-7: No established human timeline. Animal data suggests initial immune cell priming during the first week. Zinc status should be optimized concurrently.
03
Evidence
HumanModerate
AnimalPresent
In-vitroPresent
Each reference below was re-fetched from its PubMed record, and the quoted sentence was
confirmed to appear in that abstract and to support the claim it sits under. Follow any of
them to read the source.
Exact-molecule evidence boundary: the live abstract reports the quoted finding for Thymulin; no broader inference is made.
Thymulin (formerly called FTS) is a well defined nonapeptide hormone produced by thymic epithelial cells.
Evidence scope. Exact molecule wording appears in the quoted live sentence. Only the population/model, formulation, route, and outcome expressly stated there are supported.
Claims we could not support
No abstract we checked supports these for this molecule at this route. That is not the
same as saying they are false — it marks where the evidence is missing.
Dose/route: Per protocol; Subcutaneous (SubQ); Daily. No selected live abstract sentence verified this complete regimen.
Mechanism as written in source JSON. No selected live abstract sentence verified the complete mechanism at the card formulation/route and relevant population/model.
Primary safety claim as written in source JSON. No selected live abstract sentence verified the complete safety claim for this exact formulation and route.
04
Interactions & stacking
Two different questions: what is documented about running these together, and what is documented about drawing them into the same syringe. A good pharmacological partner can still have to be pinned separately.
Documented together
BPC-157Tissue repair peptide and thymic immune peptide act through independent systems
EpithalonTelomerase activation and thymic immune function address different aging pathways
SelankAnxiolytic and immunomodulatory peptide does not conflict with thymic T-cell maturation
LL-37Antimicrobial defense peptide and T-cell maturation peptide provide complementary immune support
GHK-CuCopper-peptide complex may compete with zinc binding essential for thymulin bioactivity, or cause metal-exchange inactivation - do not mix
EDTAChelating agents strip the zinc ion required for thymulin activity, rendering it biologically inactive
Check any specific pair in the Stack & Interaction Checker, which answers both questions separately. Absence of a documented conflict is not evidence of safety.
05
Pharmacokinetics
Illustrative plasma concentration · 16 h
Half-life
~minutes (rapidly cleared nonapeptide)
Peak · Tmax
~10-20 min
SubQ
Elimination
~1-2 hours
Bioavailability
~80-90%
SubQ (estimated; zinc-dependent bioactivity)
Duration of action
1-2 days
T-cell differentiation signals outlast plasma presence; zinc status modulates duration