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Hormonal Dietary supplementLepidium meyenii (Peruvian Maca Root)

Maca

Maca Root · Lepidium meyenii

1.5-3g daily – 2000-3000 mg Oral 1-2x daily
Adaptogen / Energy SupportLibido and Fertility Botanical

Maca (Lepidium meyenii) is a Peruvian root vegetable from the Andes mountains, traditionally consumed for energy, fertility, and libido support. Multiple color phenotypes exist: yellow (most common, balanced effects), red (predominantly studied for prostate health), and black (predominantly studied for energy and male fertility).

Quick Start
Route
Oral powder or capsule
Start low
1.5-3g Oral
Frequency
1-2x daily
Timing
Independent (food typical for tolerance)

Morning common; some users split AM/PM. Avoid evening if energizing effect.

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first
Conservative start
1.5-3g daily · Oral powder or capsule · 1-2x daily
conservative starter
1.5-3g daily
1-2x daily
Standard
Libido & Vitality
2000-3000 mg · Oral · Daily
human clinical trial · Gonzales et al. 2002 (Andrologia)
Gelatinized maca is vastly preferred to raw maca powder to avoid intense gastrointestinal distress.
2000-3000 mg
Daily
01

How it works

Maca's effects do NOT come from direct hormonal modulation:

Hormonal Neutrality

Multiple controlled studies show maca does NOT increase serum testosterone, estradiol, FSH, or LH levels. The libido and energy effects occur via different pathways.

Macamides

Unique fatty acid amides found in maca that act on cannabinoid (CB1) and TRPV1 receptors. May mediate libido, mood, and adaptogen effects.

Hypothalamic-Pituitary Effects

May modulate HPA and HPG axes at the hypothalamic level rather than peripherally.

Sperm Parameters

In male fertility, maca improves sperm count and motility through unclear mechanisms - likely involves mitochondrial energy metabolism in sperm.

Color Phenotype Differences

Red maca shows specificity for prostate health; black maca for male fertility/energy; yellow is balanced. Likely reflects differential bioactive content.

02

What to expect

Early
Days 1–7

Days 1-14: subtle subjective effects.

Mid
Weeks 2–4

Weeks 2-8: peak libido and energy effects.

Later
Weeks 4–12

Weeks 8+: sustained effects; sperm parameter improvements need 12+ weeks.

03

Evidence

HumanPresent
AnimalPresent
In-vitroPresent

Each reference below was re-fetched from its PubMed record, and the quoted sentence was confirmed to appear in that abstract and to support the claim it sits under. Follow any of them to read the source.

Evidence boundary from the checked abstract: Increase of sperm count was not related to dose of Maca.

Increase of sperm count was not related to dose of Maca.

Lepidium meyenii (Maca) improved semen parameters in adult men. Asian journal of andrology · 2001 · PMID 11753476

Evidence scope. This entry supports only the exact statement quoted from the live abstract; it does not independently verify OnePin's displayed dose, route, frequency, formulation, population, or broader mechanism.

Claims we could not support

No abstract we checked supports these for this molecule at this route. That is not the same as saying they are false — it marks where the evidence is missing.

Dose/route: 1.5-3g daily; Oral powder or capsule; 1-2x daily. No checked live PubMed abstract verified this exact displayed dose, route, and frequency for the same molecule/formulation and relevant population.

Primary safety claim: No primary safety text present in source JSON. No checked live PubMed abstract directly verified this source-JSON safety claim at the displayed formulation, route, and regimen.

04

Side effects & safety

Commonly reported

  • Mild GI upset (especially raw maca)
  • Mild stimulant effect

Less common & notes

  • Goitrogenic compounds in raw maca may affect thyroid at very high doses - cooking/gelatinization eliminates concern.
  • Allergic reactions rare.
  • Long-term safety good per traditional Andean dietary use.
05

Pharmacokinetics

Illustrative plasma concentration · 18 h
Half-life

Variable by component

Peak · Tmax
1-3 hours
Elimination

Hours plasma; effects accumulate over weeks

Bioavailability

Oral moderate; gelatinized higher

Duration of action

Days for cumulative effects

Clearance

Hepatic

Storage. Powder/capsule. Cool, dry location. Sealed container.

06

Regulatory status

Dietary supplement (US, DSHEA). Traditional food in Peru.

Put it to work

Calculate, log & track

Open Maca straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

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Go deeper

The guide & community

The complete Maca walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

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