library.onepin.app/bronchogen Peptide Education Library
Education only, not medical advice 21+ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Bioregulators

Bioregulators Bioregulator Not FDA-approved · investigational

Bronchogen

Bronchogen (Khavinson)

Bioregulator

Bronchogen is a synthetic tripeptide bioregulator (Ala-Glu-Asp) developed by Professor Vladimir Khavinson at the Saint Petersburg Institute of Bioregulation and Gerontology. It belongs to the Khavinson peptide bioregulator class, which are short peptides designed to target specific tissues. Bronchogen is designed to act on bronchial and lung tissue, supporting respiratory epithelial function and mucosal integrity.,Khavinson bioregulators are based on the theory that short peptides can interact with DNA and regulate gene expression in a tissue-specific manner. Bronchogen is part of a broader family of bioregulators studied primarily in Russian research institutions. Published studies have appeared in Russian medical journals, though large-scale Western clinical trials are lacking.,Bronchogen remains a research compound without regulatory approval from the FDA or EMA. Most available evidence comes from small Russian clinical studies and preclinical work. It is used in complementary protocols by practitioners familiar with the Khavinson bioregulator system.

Quick Start
Route
Subcutaneous (SubQ)
Start low
1-10mg
Frequency
daily
Timing
No specific requirement

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first
Quick Start
Conservative start
1-10mg · Subcutaneous (SubQ) · daily
Lowest starting point. Hold about a week to assess tolerance before stepping up.
1-10mg
daily
Standard
Pulmonary Bioregulator
10-20 mg · Oral · Daily
animal study · Kuzubova et al. 2015 (Bull Exp Biol Med 159(5):685-688, PMID 26468022)
10-20 mg
Daily
Intermediate
Injectable Respiratory Repair
5-10 mg · IM · Daily
anecdotal · community
5-10 mg
Daily
Reconstitution CalculatorU-100
050100u
Draw to
units
01

How it works

Proposed to interact with DNA regulatory sequences in bronchial epithelial cells, modulating gene expression related to tissue repair and mucosal defense.,May upregulate synthesis of surfactant proteins and mucins that maintain airway surface integrity and immune barrier function.,Theorized to normalize peptide regulation in aged or damaged lung tissue, restoring protein synthesis patterns characteristic of younger, healthier tissue.

Proposed to interact with DNA regulatory sequences in bronchial epithelial cells, modulating gene expression related to tissue repair and mucosal defense.,May upregulate synthesis of surfactant proteins and mucins that maintain airway surface integrity and immune barrier function.,Theorized to normalize peptide regulation in aged or damaged lung tissue, restoring protein synthesis patterns characteristic of younger, healthier tissue.

02

What to expect

Early
Days 1–7

Days 1-7: Minimal perceptible effects. Cellular-level changes in bronchial tissue may be occurring but are not typically felt.

03

Evidence

HumanModerate
AnimalPresent
In-vitroPresent
2010Peptide bioregulation of aging: results and prospects · Anisimov VN, Khavinson VK, Biogerontology ↗review
2013Peptide bioregulators: the new class of geroprotectors. Communication 1. Results of experimental studies · Khavinson VK, Kuznik BI, Advances in Gerontology ↗review
2013Peptide bioregulators: the new class of geroprotectors. Message 2. Clinical studies results · Khavinson VK, Kuznik BI, Advances in Gerontology ↗review
2000Application of peptide bioregulators in gerontology: results and perspectives · Khavinson VK et al, Bulletin of Experimental Biology and Medicine ↗review
04

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Keep separate

CJC-1295 with DACDo not mix in same syringe.
05

Pharmacokinetics

Illustrative plasma concentration · 24 h
Half-life
Minutes (tiny peptide)
Peak · Tmax
15-30 min SubQ
Elimination
~1-2 hours
Activity
Days to weeks (gene expression changes in bronchial tissue persist long after peptide clearance)

Storage. Store refrigerated at 2-8C.

06

Regulatory status

Unregulated research peptide. Not approved by FDA, EMA, or other major regulatory bodies. Used primarily within the Khavinson bioregulator framework in Russia and by integrative medicine practitioners.

Put it to work

Calculate, log & track

Open Bronchogen straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Bronchogen in the app →

Go deeper

The guide & community

The complete Bronchogen walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

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