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OnePin Peptide Library · Immune

Immune Astragalus membranaceus (Huang Qi - TCM)

Astragalus

Astragalus membranaceus

Astragalus membranaceus (Huang Qi - TCM)Adaptogen / Immune ModulatorTelomerase Activator (TA-65 form)Dietary Supplement

Astragalus (Astragalus membranaceus / Huang Qi) is a TCM adaptogen used for centuries to support immune function, energy, and longevity. The root contains polysaccharides (astragalan), saponins (astragalosides), and flavonoids as primary bioactives.

Quick Start
Route
Oral capsule or tincture
Start low
500mg-1g daily
Frequency
1-2x daily
Timing
Independent

Morning preferred.

❋

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first
Quick Start
Conservative start
500mg-1g daily · Oral capsule or tincture · 1-2x daily
Lowest starting point. Hold about a week to assess tolerance before stepping up.
500mg-1g daily
1-2x daily
Standard
Telomere & Immune Support
500-1000 mg · Oral · Daily
in vitro · Fauce et al. 2008 (J Immunol, 181(10):7400-7406)
500-1000 mg
Daily
◆
01

How it works

Astragalus has multiple bioactive compound classes:

Astragalus Polysaccharides (APS)

Immune-modulating - activate macrophages, NK cells, T-cells. Adaptogenic effects on stress resistance.

Astragaloside IV

Cardioprotective effects in animal heart failure models. Anti-fibrotic and anti-apoptotic in cardiomyocytes.

TA-65 (Cycloastragenol-Concentrated)

Refined product targeting telomerase activation. Small clinical trials in immunosenescent populations show modest effects on telomere length and immune markers.

Saponin Cardiovascular Effects

BP modulation, vascular endothelial support.

Anti-Inflammatory

NF-κB modulation similar to other adaptogens.

02

What to expect

Early
Days 1–7

Days 1-14: subtle subjective effects.

Mid
Weeks 2–4

Weeks 2-12: peak adaptogen and immune effects.

Later
Weeks 4–12

Long-term: continuous use traditional.

03

Evidence

HumanPresent
AnimalStrong
In-vitroPresent
2011A natural product telomerase activator as part of a health maintenance program · Harley CB et al, Rejuvenation Research ↗peer reviewed
2016Astragalus membranaceus: a review of its protection against inflammation and gastrointestinal cancers · Auyeung KK et al, American Journal of Chinese Medicine ↗review
2017Astragalus membranaceus: a review of its bioactivities and potential clinical applications · Liu P et al, Phytotherapy Research ↗review
04

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Keep separate

05

Side effects & safety

Commonly reported

  • Mild GI
  • Mild allergic skin reactions

Less common & notes

  • Theoretical immune-stimulating concern in autoimmune disease - relative caution.
  • Long-term safety good per TCM use.
06

Pharmacokinetics

Illustrative plasma concentration · 24 h
Half-life
Variable by component
Peak · Tmax
1-3 hours
Elimination
Days for cumulative effects
Activity
Continuous use traditional

Storage. Capsule/tincture. Cool dry location.

07

Regulatory status

Dietary supplement (US, DSHEA). TCM in Asian markets.

Put it to work

Calculate, log & track

Open Astragalus straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Astragalus in the app →

Go deeper

The guide & community

The complete Astragalus walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗
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