library.onepin.app/adamax Peptide Education Library
Education only, not medical advice 21+ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Cognitive & Mood

Cognitive & Mood Russian Synthetic Neuropeptide Not FDA-approved · investigational

Adamax

Russian Synthetic NeuropeptideAnxiolytic Research PeptideLimited Western LiteratureResearch Chemical

Adamax is a Russian-developed synthetic peptide neuroregulator, structurally derived from a brain peptide and sharing chemistry with the broader Russian neuropeptide family (Selank, Semax, Cortagen, Cortexin). Specifically: Adamax is a tetra/heptapeptide with anxiolytic, neurotrophic, and modest cognitive effects in Russian Federation research settings. Limited Western clinical literature; available as a research chemical primarily through Russian and Eastern European peptide suppliers.

Quick Start
Route
Intranasal (primary) or SubQ
Start low
100-200mcg per nostril
Frequency
1-2x daily
Timing
Independent

Intranasal application morning and/or pre-stress event. Reconstitute with bac water for nasal solution; refrigerate.

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first
Quick Start
Conservative start
100-200mcg per nostril · Intranasal (primary) or SubQ · 1-2x daily
Lowest starting point. Hold about a week to assess tolerance before stepping up.
100-200mcg per nostril
1-2x daily
Expert
Cognitive Enhancement
100-200 mcg · Nasal · Daily
anecdotal · community
100-200 mcg
Daily
Reconstitution CalculatorU-100
050100u
Draw to
units
01

How it works

Adamax mechanism is incompletely characterized in Western literature. Russian publications describe:

GABA Modulation

Like Selank, modest GABAergic activity contributing to anxiolytic effects.

BDNF Upregulation

Reported to increase BDNF expression in rodent brain - mechanistic basis for putative neurotrophic claims.

Stress Resistance

Improved performance on stress-paradigm tests in rodents (forced swim, elevated plus maze).

Linear Peptide Stability

Linear short peptide; reasonably stable in storage. No Met or Cys residues - no GHK-Cu chemistry conflict.

Intranasal CNS Access

Like Selank/Semax, intranasal route enables direct nasal-to-brain transport bypassing the blood-brain barrier.

02

What to expect

Early
Days 1–7

Days 1-7: subtle anxiolytic onset.

Mid
Weeks 2–4

Weeks 1-2: peak anxiolytic and putative neurotrophic effect.

Later
Weeks 4–12

Weeks 2-4: end of typical cycle; effects fade after discontinuation.

03

Evidence

HumanModerate
AnimalModerate
In-vitroPresent
2014Synthetic peptides as drugs (Russian neuropeptide context) · Khavinson VK et al, Bulletin of Experimental Biology and Medicine ↗review
2009Russian peptide pharmacology in CNS disorders · Mendzheritsky AM, Kovalev GI, Neurochemical Journal ↗review
2008Selank and Semax: synthetic peptides with ACTH 4-10 and Tuftsin lineage · Zozulya AA, Volker N, Voprosy Pitaniya (Russian) ↗review
04

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Keep separate

05

Side effects & safety

Commonly reported

  • Mild nasal irritation (intranasal route)
  • Mild headache (early doses)
  • Possible mild sedation

Less common & notes

  • Long-term safety not characterized in Western populations.
  • Allergic reactions rare.
  • Russian neuropeptide class has generally good safety profile in published literature but Western-grade safety data is limited.
06

Pharmacokinetics

Illustrative plasma concentration · 24 h
Half-life
~2-4 hours plasma
Peak · Tmax
1-2 hours post-dose
Elimination
4-8 hours functional
Activity
4-8 hours per dose; cumulative effects over weeks

Storage. Refrigerate. Reconstituted: 21-28 days.

07

Regulatory status

Not FDA-approved. Available in Russian Federation as research / OTC nutraceutical context. Western use is research-chemical only.

Put it to work

Calculate, log & track

Open Adamax straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Adamax in the app →

Go deeper

The guide & community

The complete Adamax walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗
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