library.onepin.app/green-tea-extract-egcg Peptide Education Library
Education only, not medical advice 21+ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Metabolic

Metabolic Peptide

Green Tea Extract (EGCG)

EGCG · Camellia sinensis Extract

Oral only. Standardized to 45-50% EGCG typically. Cardioprotective, anti-inflammatory, thermogenic. Caffeine-containing (unless decaf) - dose calculation needed if stacking with coffee. HEPATOTOXICITY WARNING at high doses on empty stomach - take WITH FOOD. Avoid if liver impairment. CYP3A4 mild inhibition.

Quick Start
Route
Oral capsule
Start low
200-400mg EGCG
Frequency
1-2x daily
Timing
MANDATORY with food (hepatotoxicity risk on empty stomach)

With meals, AM or split AM/PM

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first
Quick Start
Conservative start
200-400mg EGCG · Oral capsule · 1-2x daily
Lowest starting point. Hold about a week to assess tolerance before stepping up.
200-400mg EGCG
1-2x daily
Standard
Metabolic Enhancement
400-800 mg · Oral · Daily
human clinical trial · Dulloo et al. 1999 (Am J Clin Nutr)
400-800 mg
Daily
01

What to expect

Early
Days 1–7

First days to weeks: any focus or energy lift comes from caffeine content and is felt acutely; antioxidant effects are not something you feel.

Mid
Weeks 2–4

Weeks 4-8: metabolic and antioxidant support accrues with consistent daily use alongside diet and activity.

Later
Weeks 4–12

Ongoing: a long-game supportive supplement; benefits are maintenance-oriented rather than escalating.

02

Evidence

2007Effects of green tea and EGCG on cardiovascular and metabolic health · Wolfram S, Journal of the American College of Nutrition ↗review
2023The effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis · Xu R, Yang K, Li S, Dai M, Chen G, Frontiers in Nutrition ↗review
2007A green tea extract high in catechins reduces body fat and cardiovascular risks in humans · Nagao T, Hase T, Tokimitsu I, Obesity ↗trial registry
2007EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR · Potenza MA, Marasciulo FL, Tarquinio M, et al, American Journal of Physiology - Endocrinology and Metabolism ↗peer reviewed
03

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Safe & synergistic

CurcuminComplementary anti-inflammatory polyphenols. Classic longevity stack.
FisetinBoth polyphenol class. Complementary senolytic/antioxidant.
L-TheanineGreen tea naturally contains both - clinical studies use EGCG+L-theanine combo for cognition.
04

Pharmacokinetics

Illustrative plasma concentration · 24 h
Half-life
~5 hours
Peak · Tmax
1-2 hours
Activity
6-8 hours polyphenol effect

Storage. [object Object]

Put it to work

Calculate, log & track

Open Green Tea Extract (EGCG) straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Green Tea Extract (EGCG) in the app →

Go deeper

The guide & community

The complete Green Tea Extract (EGCG) walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

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