OnePin Peptide Library · Joints
Boswellia
Boswellia serrata · Frankincense Extract
Boswellia (Boswellia serrata, also known as Indian Frankincense) is a tree resin extract used in Ayurvedic medicine for centuries. Active compounds are boswellic acids, particularly AKBA (3-O-acetyl-11-keto-β-boswellic acid) - a potent and selective 5-lipoxygenase inhibitor that reduces leukotriene-mediated inflammation.
Independent.
Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.
How it works
Boswellia acts via boswellic acids:
AKBA 5-LOX Inhibition
AKBA selectively inhibits 5-lipoxygenase, reducing leukotriene B4 and other pro-inflammatory leukotrienes - distinct from NSAIDs (which inhibit COX). Complementary mechanism.
NF-κB Modulation
Boswellic acids reduce NF-κB activation, decreasing inflammatory cytokine production.
Cathepsin G Inhibition
Reduces neutrophil-mediated tissue damage.
Synovial Fluid Effects
Improves joint synovial fluid composition in OA.
Better GI Tolerance
Unlike NSAIDs (COX inhibition causes GI ulceration), boswellia's 5-LOX mechanism doesn't compromise gastric protection.
What to expect
Days 1-14: subtle effects.
Weeks 4-8: peak benefits.
Long-term continuous use OK.
Evidence
Interactions & stacking
What's safe to combine, and what belongs in a separate pin.
Keep separate
Side effects & safety
Commonly reported
- Mild GI
- Mild headache rare
Less common & notes
- Mild antiplatelet activity.
- Allergic reactions rare.
- Long-term safety good per Ayurvedic use.
Pharmacokinetics
Storage. Capsule. Cool dry location.
Regulatory status
Dietary supplement (US, DSHEA). Ayurvedic medicine.
Put it to work
Calculate, log & track
Open Boswellia straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.
Open Boswellia in the app →Go deeper
The guide & community
The complete Boswellia walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.
Join the community ↗