library.onepin.app/arnica Peptide Education Library

Education only, not medical advice◆ 21+◆ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Repair & Recovery

Repair & Recovery Botanical

Arnica

Arnica montana · Leopard's Bane · Mountain Arnica · Wolf's Bane

BotanicalAnti-inflammatory (topical)

Botanical from the Arnica montana plant. Primary evidence base supports TOPICAL use (gel/cream/ointment) for bruising, sprains, muscle soreness, and post-procedure swelling. Oral whole-plant arnica is TOXIC (cardiotoxic) and must NEVER be ingested - only highly diluted homeopathic preparations (Arnica 30C / 200C pellets) are oral-safe but have limited mechanistic evidence. Active compounds are sesquiterpene lactones (helenalin, dihydrohelenalin) plus flavonoids.

Quick Start

Route

Topical gel

Start low

Pea-sized amount per affected area, 7% arnica gel

Frequency

2-4x daily

Timing

N/A (topical)

Apply at onset of symptoms; continue 3-7 days. Combine with bromelain orally for post-surgical stack.

❋

Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first

Quick Start

Conservative start

Pea-sized amount per affected area, 7% arnica gel · Topical gel · 2-4x daily

Lowest starting point. Hold about a week to assess tolerance before stepping up.

Pea-sized amount per affected area, 7% arnica gel

2-4x daily

Standard

Topical Recovery Gel

20 % · Topical · As needed

human clinical trial · Widrig et al. 2007 (Rheumatol Int)

20 %

As needed

◆

How it works

Sesquiterpene lactones (helenalin, dihydrohelenalin) inhibit NF-κB signaling, reducing inflammatory cytokine cascade locally at site of application,Inhibits transcription factors driving inflammation in keratinocytes and immune cells,Flavonoids and carotenoids contribute antioxidant activity at the application site,Topical penetration localizes activity - minimal systemic exposure with intact skin

What to expect

Early

Days 1–7

Hours to days: applied topically to a fresh bruise or sore area, many notice reduced tenderness and swelling within the first day or two.

Mid

Weeks 2–4

Days 3-7: with repeated application, discoloration generally fades faster than untreated and soreness continues to ease.

Later

Weeks 4–12

Beyond a week: best suited to short-term use around injuries, procedures, or hard training rather than continuous daily application.

Evidence

2007Topical Arnica gel vs ibuprofen gel for hand osteoarthritis: a randomized, double-blind study · Widrig R et al, Rheumatology International ↗peer reviewed

2014The effects of topical Arnica on performance, pain and muscle damage after intense eccentric exercise · Pumpa KL et al, European Journal of Sport Science ↗peer reviewed

2014Arnica montana effects on muscle damage induced by eccentric exercise · Pumpa KL et al, Phytotherapy Research ↗peer reviewed

2016Homeopathic Arnica montana for post-surgical bruising and pain: systematic review · Iannitti T et al, American Journal of Therapeutics ↗review

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Safe & synergistic

BromelainCommon post-surgical combo: topical arnica reduces local bruising while oral bromelain provides systemic anti-inflammatory and edema-reduction support. Used together post-rhinoplasty, dental surgery, sports injuries.

Vitamin CSupports collagen repair and capillary integrity. Often paired post-injury to reduce bruising tendency.

Vitamin KVitamin K cream + arnica gel stack commonly used pre/post cosmetic procedures (filler, laser) to minimize bruising.

BPC-157Peptide BPC-157 (oral or injectable) for tissue repair pairs with topical arnica for symptomatic surface bruising/soreness. Complementary mechanisms (systemic angiogenesis vs local NF-κB inhibition).

Pharmacokinetics

Illustrative plasma concentration · 24 h

Half-life

Topical: local effect, minimal systemic absorption with intact skin

Peak · Tmax

Topical: 30-60 min for local peak; homeopathic pellets: dissolves under tongue in 1-2 min

Activity

Topical gel: 4-6 hours per application; reapply 2-4x daily for sustained effect

Storage. [object Object]

Put it to work

Calculate, log & track

Open Arnica straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Arnica in the app →

Go deeper

The guide & community

The complete Arnica walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗

Open in app Community