Lipo-C/MIC
MIC · Lipo-MIC · Methionine Inositol Choline · Lipotropic
Lipo-C/MIC is a lipotropic injection blend containing methionine, inositol, and choline (the 'MIC' components) along with cyanocobalamin (vitamin B12) and often L-carnitine. These compounds are classified as lipotropic agents - substances that promote the breakdown and metabolism of fat in the body. The injection is widely used in weight management clinics and integrative medicine practices as an adjunct to diet and exercise programs.
Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.
How it works
Methionine, inositol, and choline act as lipotropic agents that promote hepatic fat metabolism: methionine provides methyl groups for metabolic reactions, inositol aids fat transport and insulin signaling, and choline is required for VLDL synthesis and fat export from the liver.
Vitamin B12 (cyanocobalamin) serves as a cofactor for methionine synthase and methylmalonyl-CoA mutase, supporting energy metabolism, methylation reactions, and red blood cell production.
L-carnitine (when included) facilitates transport of long-chain fatty acids into mitochondria for beta-oxidation, directly supporting fat utilization for energy.
What to expect
Days 1-7: Energy boost from B12. Mild improvement in alertness and mood. Fat metabolism effects building.
Evidence
Claims we could not support
No abstract we checked supports these for this molecule at this route. That is not the same as saying they are false — it marks where the evidence is missing.
Dose/route: 1mL; Intramuscular (IM); weekly. No checked live PubMed abstract verified this exact displayed dose, route, and frequency for the same molecule/formulation and relevant population.
Mechanism: Methionine, inositol, and choline act as lipotropic agents that promote hepatic fat metabolism: methionine provides methyl groups for metabolic reactions, inositol aids fat transport and insulin signaling, and choline is required for VLDL synthesis and fat export from the liver.. No checked live PubMed abstract provided an exact-molecule/formulation sentence supporting this source-JSON mechanism claim.
Primary safety claim: Injection site pain, redness, or swelling. No checked live PubMed abstract directly verified this source-JSON safety claim at the displayed formulation, route, and regimen.
Interactions & stacking
Two different questions: what is documented about running these together, and what is documented about drawing them into the same syringe. A good pharmacological partner can still have to be pinned separately.
Documented together
Keep separate
Check any specific pair in the Stack & Interaction Checker, which answers both questions separately. Absence of a documented conflict is not evidence of safety.
Pharmacokinetics
Varies by component: B12 ~6 days (tissue retention), methionine ~2-3 hours, choline ~hours, inositol ~hours
(IM). Variable by component.
Variable by component. Methionine/choline/inositol cleared within ~12-24 hours. B12 retained in tissues for weeks.
IM. Bypasses variable oral absorption of individual components.
Metabolic effects; B12 tissue effects persist for days to weeks
Hepatic metabolism and renal (methionine/choline/inositol rapidly metabolized; B12 stored hepatically)
Storage. Store refrigerated at 2-8C. Protect from light. B12 is light-sensitive.
Regulatory status
Compounded preparation - not FDA-approved as a specific drug product. Individual components (B12, methionine, inositol, choline) are established nutrients. Available through compounding pharmacies by prescription. Typically administered alone - do not mix with other injectable compounds.
Put it to work
Calculate, log & track
Open Lipo-C/MIC straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.
Open Lipo-C/MIC in the app →Go deeper
The guide & community
The complete Lipo-C/MIC walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.
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