library.onepin.app/testagen Peptide Education Library

Education only, not medical advice◆ 21+◆ Every dose is an example to finalize with a licensed provider

OnePin Peptide Library · Bioregulators

Bioregulators Khavinson bioregulator tetrapeptide Not FDA-approved · investigational

Testagen

Testagen (Khavinson)

Khavinson bioregulator tetrapeptideTesticular tissue regulatorGene expression modulator

Testagen (Lys-Glu-Asp-Gly) is a Khavinson bioregulator tetrapeptide targeting testicular tissue gene expression. It supports Leydig cell function, Sertoli cell maintenance, and testicular hormone production pathways. Complementary to HCG (direct LH receptor stimulation) for comprehensive testicular support during TRT.

Quick Start

Route

SubQ injection

Start low

5 mg daily

Frequency

Daily for 10-20 day course

Timing

No fasting required

SubQ injection, any time of day. 10-20 day courses, 2-3 cycles per year with 4-6 months between courses (Khavinson protocol). Pin alone or with other bioregulators only.

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Start here. Every protocol below is ordered lowest-first. Begin at the smallest effective dose, hold about a week to assess tolerance, and step up only if needed.

Tiered Protocols · lowest first

Quick Start

Conservative start

5 mg daily · SubQ injection · Daily for 10-20 day course

Lowest starting point. Hold about a week to assess tolerance before stepping up.

5 mg daily

Daily for 10-20 day course

Standard

Testicular Bioregulation

10-20 mg · Oral · Daily

animal study · Khavinson et al., Advances in Gerontology, 2010

10-20 mg

Daily

Reconstitution CalculatorU-100

Vial strength

BAC water

Target dose

050100u

Draw to

— units

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How it works

Testagen modulates gene expression in testicular tissue (Leydig cells, Sertoli cells), supporting steroidogenic enzyme expression, LH receptor sensitivity, and spermatogenic support pathways at the gene level.

What to expect

Early

Days 1–7

Days 1-10: Gene changes initiated.

Mid

Weeks 2–4

Weeks 2-8: Testicular gene programs established.

Later

Weeks 4–12

Months: Sustained testicular tissue support.

Evidence

HumanPresent

AnimalPresent

In-vitroPresent

2003Peptides of pineal gland and thymus prolong human life · Khavinson VK, Morozov VG, Neuro Endocrinology Letters ↗peer reviewed

2013Peptide bioregulators: the new class of geroprotectors. Message 2. Clinical studies results · Khavinson VK et al, Advances in Gerontology ↗review

The honest take

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Testicular rejuvenation

Bioregulatory gene expression modulation targeting testicular tissue. Complementary to direct hormonal stimulation (HCG).

Interactions & stacking

What's safe to combine, and what belongs in a separate pin.

Safe & synergistic

HCGTestagen targets testicular gene expression, HCG stimulates Leydig cells directly. Complementary testicular support.

ProstamaxTestagen testicular + Prostamax prostate. Complementary male reproductive support. Run in sequence.

Keep separate

ALL (syringe)PIN ALONE.

GHK-CuCopper degrades bioregulators.

Side effects & safety

Commonly reported

Very well tolerated

Less common & notes

Monitor testosterone and estradiol if on TRT.
Excellent safety profile.

Pharmacokinetics

Illustrative plasma concentration · 24 h

Half-life

0.5h

Peak · Tmax

0.05h

Elimination

2.5h

Activity

Weeks to months (epigenetic gene expression changes persist beyond dosing course)

Storage. Standard BAC water 2-8C. 21-28 days.

Regulatory status

Not FDA-approved. Research peptide.

Put it to work

Calculate, log & track

Open Testagen straight into OnePin with your vial and dose pre-filled, then let it handle the syringe math and remind you before the vial runs out.

Open Testagen in the app →

Go deeper

The guide & community

The complete Testagen walkthrough, real protocol discussion and coaching live inside the BlessUp community on Skool.

Join the community ↗

Open in app Community